Antibacterial compounds

Fungicidal activity of an antibacterial compound from entomopathogenic nematode symbiotic bacterium. by Ganpati Jagdale

Recently, Yang et al. (2011) tested a fungicidal activity of an antibacterial compound called Xenocoumacin 1 (Xcn1) from symbiotic bacterium, Xenorhabdus nematophila var. pekingensis against Potato late blight disease causing fungus, Phytophthora infestans.  These authors reported that this antibacterial compound strongly inhibits P. infestans mycelium growth and sporangia production. Read following papers on antibacterial compounds from entomopathogenic nematode symbiotic bacteria.

Akhurst, R.J. 1982.  Aantibiotic-activity of xenorhabdus spp, bacteria symbiotically associated with insect pathogenic nematodes of the families Heterorhabditidae and Steinernematidae . Journal of General Microbiology 128: 3061.

Bowen, D. 1998. Insecticidal toxins from the bacterium Photorhabdus luminescens. Science 280 : 2129.

Fang, X. L., Feng, J.T., Zhang, W. G., Wang, Y. H. and Zhang, X. 2010.  Optimization of growth medium and fermentation conditions for improved antibiotic activity of Xenorhabdus nematophila TB using a statistical approach.  African Journal of Biotechnology: 9: 8068-8077.

Gualtieri, M. 2009. Identification of a new antimicrobial lysine-rich cyclolipopeptide family from Xenorhabdus nematophila. Journal of Antibiotics 62: 295.

Ji, D. 2004. Identification of an antibacterial compound, benzylideneacetone, from Xenorhabdus nematophila against major plant-pathogenic bacteria. FEMS Microbiology Letters 239: 241.

Li, J.X. 1995. Antimicrobial metabolites from a bacterial symbiont. Journal of Natural Products-Lloydia 58: 1081.

Li, J.X. 1997. Nematophin, a novel antimicrobial substance produced by Xenorhabdus nematophilus (Enterobactereaceae). Canadian Journal of Microbiology 43: 770.

Mcinerney, B.V. 1991. Biologically-active metabolites from Xenorhabdus spp .1. dithiolopyrrolone derivatives with antibiotic-activity. Journal of Natural Products 54: 774.

Mcinerney, B.V. 1991. Biologically-active metabolites from Xenorhabdus spp.2. BENZOPYRAN-1-ONE derivatives with gastroprotective activity. Journal of Natural Products 54: 785.

Paul, V.J. 1981. Antibiotics in microbial ecology - isolation and structure assignment of several new anti-bacterial compounds from the insect-symbiotic bacteria Xenorhabdus Spp. Journal of Chemical Ecology 7: 589.

Wang, Y.H.  2008. Enhanced antibiotic activity of Xenorhabdus nematophila by medium optimization. Bioresource Technology 99: 1708.

Yang , X.F., Qiu, D.W., Yang, H.W., Liu, Z., Zeng, H.M. and Yuan, J.J.  2011.  Antifungal activity of xenocoumacin 1 from Xenorhabdus nematophilus var. pekingensis against Phytophthora infestans . World Journal of Microbiology and Biotechnology 27: 523-528.